Archive

Archive for March, 2010

FY09 Net Loss Narrows, Opexa Therapeutics (NASDAQ: OPXA)

March 9th, 2010 No comments

Opexa Therapeutics reported (3/5/10)  a net loss of $1.43 M or $0.11 per diluted share for FY09 compared to $11.85 M or $1.12 per diluted share in FY08.  FY09 highlights:

  • The pivotal point in the year was the completion of the stem cell transaction with Novartis (NVS) Pharmaceuticals for an upfront payment of $3 M and potential technology transfer milestone payments totaling another $1 M (with total potential payments from the deal that could exceed $50 M),

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Another Milestone, Aastrom Biosciences (NASDAQ: ASTMD)

March 9th, 2010 No comments

 ASTMD reported the final patient treatment in the ongoing cardiac regeneration US P 2 surgical clinical trial designated IMPACT-DCM. Treated at Emory University Hospital Midtown in Atlanta, GA, this patient received direct injections of ASTMD’s tissue repair cells for the treatment of dilated cardiomyopathy (DCM), a severe form of congestive heart failure in which the heart becomes weakened and enlarged and cannot pump blood efficiently.

  • With the treatment of the final patient in this trial, Aastrom is positioned to report 6 month interim data on all enrolled patients in late 2010.

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Updating, Aastrom Biosciences (ASTMD) Regains NASDAQ Listing Compliance

March 5th, 2010 No comments

ASTMD has regained compliance with the $1.00 minimum bid price requirement under the NASDAQ Listing Rule.

  • On 2/18/10, ASTMD affected a reverse stock split to increase the per-share trading price of its common stock to meet the NASDAQ requirement,
  • The ticker symbol for Aastrom Biosciences will revert from ASTMD to ASTM on 3/18/10.

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Updating GERN, Collaboration with Corning Launches for Growing hESCs

March 4th, 2010 No comments

Geron’s (GERN) collaboration with Corning launches Synthemax™ surface, a novel synthetic surface supporting the growth and differentiation of stem cells and growing hESCs.

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Updating, Pluristem Therapeutics (PSTI), DSMB Approval for Critical Limb Ischemia (CLI) Trial

March 3rd, 2010 No comments

PSTI (3/2/10) received approval from an independent Data Safety Monitoring Board (DSMB) to advance its placenta-derived cell therapy product, PLX-PAD.

  • This Phase I study in the EU is to evaluate the safety of PLX-PAD for 3 dosing levels in 15 patients for the treatment of Critical Limb Ischemia (CLI), the end-stage of peripheral artery disease (PAD).

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Orphan Drug Status Granted for Treatment of Stargardt’s Macular Dystrophy, Advanced Cell Technology (OTC BB: ACTC.OB)

March 2nd, 2010 No comments

The FDA has granted Orphan Drug designation for Advanced Cell Technology‘s (ACTC.OB) MA09-hRPE cells for use in the treatment of Stargardt’s Macular Dystrophy (SMD). As a result, ACTC.OB is eligible to receive a number of benefits, including tax credits, access to grant funding for clinical trials, accelerated FDA approval and allowance for marketing exclusivity after drug approval for a period of as long as 7 years.

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The Door Opens Wider for BioTime’s (BTIM) Products

March 1st, 2010 No comments

Merck KGaA agreed to buy Millipore (MIL), a supplier of drug-development equipment for biotechnology companies  for about $6 B in cash, beating a rival offer from Thermo Fisher Scientific. BTIM’s  ACTCellerate™ progenitor cell lines and ESpan™ cell growth media sell through MIL. Merck KGaA will pay $107 a share and is a Germany based company.  The offer is 13 % more than Millipore’s closing price on 2/26/10 and 50 % higher.   Millipore, based in Billerica, Massachusetts, put itself up for sale after getting an unsolicited takeover bid worth less than $95 a share from Thermo Fisher (Bloomberg).

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